Figure 5. Variable frequencies of UA & UU dinucleotides within HCV RNA ORFs.
The predicted and observed UA and UU dinucleotides frequencies for 162 HCV RNA ORFs were plotted from lowest to highest observed frequencies (isolates identified in Supplemental Data Tables 1S & 2S). Predicted UA & UU frequencies were derived using Method 1 (Black circles). For observed UA & UU dinucleotide frequencies, points on the line are colored based on the genotype of each HCV RNA ORF: red, genotype 1; blue, genotype 2 or 3; yellow, genotype 4-6. Note that HCV genotype 2 and 3 strains tend to have substantially more UA and UU dinucleotides than HCV genotype 1 strains.