Table 2.
Variation of the secondary conformational factors of HSA in the presence of PS in various pH media
| Rate, % |
||||
|---|---|---|---|---|
| pH | Factor | no PS | 0.015 mmol/l | 0.060 mmol/l PS |
| 1.81 | α-helix | 29.3 | 35.6 | 39.1 |
| β-sheet | 35.2 | 0 | 0 | |
| Turn | 4.3 | 30.1 | 32 | |
| Random coil | 31.2 | 34.3 | 29 | |
| 3.56 | α-helix | 37.8 | 42.4 | 45 |
| β-sheet | 28.6 | 0 | 0 | |
| Turn | 5.8 | 30.7 | 31.5 | |
| Random coil | 27.8 | 26.9 | 23.5 | |
| 7.40 | α-helix | 32.2 | 34.1* | 31.5† |
| β-sheet | 26 | 16.5* | 27.2† | |
| Turn | 16.4 | 20* | 15.5† | |
| Random coil | 25.4 | 29.4* | 25.8† | |
All of the solutions contained 0.030 mg/ml HSA.
Contained 0.56 μmol/l PS.
2.25 μmol/l PS.