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. 2008 Feb 1;94(3):760–771. doi: 10.1529/biophysj.107.114074

Figure 6.

Figure 6

Probability distributions of capture times from the perfect-mixing approximation and Monte Carlo calculations. (a) Linear plot for the two-dimensional case. (b) Logarithmic plot for the two-dimensional case. Here gCAPT is a histogram of Monte Carlo capture times for a single target and no traps, and gCAPT_HIER (Eq. 19) combines gCAPT with gHIER to give the distribution for one set of traps and a target, assuming a fixed escape time from the traps. The final prediction, gCAPT_HIER_ESC (Eq. 21), also takes into account the distribution of escape times from traps. The Monte Carlo result for one set of traps and target is given by gMC. The distributions gCAPT_HIER and gCAPT_HIER_ESC are of significant magnitude well beyond 3000 time steps; the cumulative distribution functions for the Monte Carlo data at 3000 time steps are 0.568 in two dimensions and 0.654 in three. (c) Ratio of the Monte Carlo distribution to the calculated distribution log gMC/log gCAPT_HIER_ESC for the two-dimensional case, the three-dimensional case, and the complete graph. For the complete graph the ratio of the log coefficients was 0.9999 ± 0.0070 for 2500 time points. In all these calculations, to get smooth histograms large runs were used (104 trap configurations and 104 tracers per trap configuration).