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4-Aminopyridine concentration-response relationships in nonpregnant (NP) and term-pregnant (P20) mouse myometrium. Non-cumulative additions of 4-AP at concentrations above 10 μM produced contractions in nonpregnant tissues (filled circles, n = 5) but not in term-pregnant tissues (open circles, n = 5). Results are presented as the mean percentage of the maximal response to 4-AP in nonpregnant tissue strips, ± S.E.M.
