Table 4.
Comparison of Selected CSF Biomarker Median Ratios between the three Study Groups
| PRO-INFLAMMATORY OR ANGIOSTATIC vs. ANTI-INFLAMMATORY OR ANGIOGENIC BIOMARKER MEDIAN RATIO | CM | SMA | NM | OVERALL P VALUE |
| TNF-α : IL-10 | 3.33 × 10-2 | 7.51 × 10-2 | 2.04 × 10-1 | NSS |
| TNF-α : IL-8 | 7.76 × 10-2 | 7.52 × 10-1 | 6.67 × 10-1 | NSS |
| TNF-α : PDGFbb | 5.05 × 10-2 | 7.56 × 10-2 | 1.53 × 10-2 | NSS |
| IP-10 : IL-10 | 10.28 | 2.07 | 3.14 | NSS |
| IP-10 : IL-8 | 23.08 | 20.12 | 10.29 | NSS |
| IP-10 : PDGFbb | 15.35 | 2.28 | 2.32 × 10-2 | 0.003 |
Median ratios of CSF levels of pro-inflammatory/angiostatic versus anti-inflammatory/angiogenic biomarkers were compared between the three disease groups; P < 0.05 considered statistically significant; NSS, not statistically significant.