Fig. 4.

Comparison of discovered complexes and modules with complexes derived experimentally (BIND and Cellzome) and complexes catalogued in MIPS. Discovered complexes are sorted by the overlap with the best-matching experimental complex (see Methods and Supporting Text). The overlap is defined as the number of common proteins divided by the number of proteins in the best-matching experimental complex. The first 31 complexes match exactly, and another 11 have overlap above 65%. Inset shows the overlap as a function of the size of the discovered complex. Note that discovered complexes of all sizes match very well with known experimental complexes. Discovered complexes that do not match with experimental ones constitute our predictions (see Discussion for details).