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. 2003 Sep 30;100(21):12253–12258. doi: 10.1073/pnas.2037852100

Table 1. General CpG island attributes.

Methylation-prone (n = 15)
Methylation-resistant (n = 47)
Attribute Mean ± SD* Range Mean ± SD* Range P value*
Length, bp 1,098.4 ± 586.0 473-2718 1,098.4 ± 630.7 228-3182 1.00
%C+G 69.6 ± 4.31 61.7-75.8 68.8 ± 4.99 57.7-78.9 0.57
CGo/CGe 0.87 ± 0.08 0.77-1.01 0.85 ± 0.08 0.66-1.01 0.29
Sp1 sites 0.47 ± 0.64 0-2 0.70 ± 0.91 0-3 0.36

Sequences were analyzed by using the NEWCPGREPORT algorithm (http://www.uk.embnet.org/Software/EMBOSS) by using a sliding window of 200 bp and a step increment of 1.

*

Groups were compared by Student's t test.

Number of occurrences per sequence based on the consensus GRGGCRGGGW.