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Mammary tumors arising in YD neu Id-deficient mice were cystic with a small rim of viable cells surrounding an acellular core. (A and B) Tumors dissected from a YD neu Id1+/+Id3+/+ mouse (A) and a YD neu Id1–/–Id3+/– mouse (B). (C and E) Hematoxylin/eosin staining of the YD neu Id1+/+Id3+/+ tumor seen in A.(D and F) Hematoxylin/eosin staining of the YD neu Id1–/–Id3+/– tumor seen in B. (Magnifications: E and F, ×400.)
