Table 1. Effects of YB-1 on transforming activities of various oncoproteins in CEF.
RCAS
|
YB-1
|
|||
---|---|---|---|---|
Oncoprotein | FFU/ml | EOT | FFU/ml | EOT |
v-Jun | 2.3 × 105 | 1.00 | 2.3 × 105 | 1.00 |
myr-P3k | 1.7 × 105 | 1.00 | 1.0 × 103 | 0.01 |
myr-Akt | 6.5 × 105 | 1.00 | 4.0 × 104 | 0.06 |
c-Qin | 1.8 × 104 | 1.00 | 2.4 × 104 | 1.33 |
v-Src | 5.7 × 105 | 1.00 | 7.5 × 105 | 1.32 |
FFU, focus-forming units; EOT, efficiency of transformation (FFU/ml on YB-1-expressing cells divided by FFU/ml on RCAS controls).