Figure 5.

Increased invasion ability of PC3 cells when transfected with ARA70β. A: ARA70β expression in PC3-ARA70β cells (top) and reduced AR expression (bottom) by AR siRNA in LNCaP cells. B: Increasing numbers of PC3 cells invade through Matrigel membrane when transfected with ARA70β as compared to pBabe vector alone control cells in regular media. C: Comparable numbers of LNCaP-ARA70β cells invade when AR is reduced by AR siRNA compared to control siRNA. D: Photomicrographs showing increased numbers of PC3 cells expressing ARA70β invading through Matrigel and forming clusters (right) relative to vector control cells (left). Original magnifications, ×400.