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. 2008 Jan;172(1):146–155. doi: 10.2353/ajpath.2008.070690

Figure 6.

Figure 6

FoxP3+ T cells are absent in MS lesions. Double-immunofluorescent staining, analyzed by confocal microscopy. A, D, G, and J: staining for CD3 (red) and B, E, H, and K: FoxP3 (blue). C, F, and I: Overlays demonstrate that FoxP3 is not expressed in CD3+ cells in perivascular cuffs from acute (C) and inactive (F) MS lesions and control brain (I). L: Overlay demonstrates in lymph nodes that some T cells express FoxP3. M: IL-17+ (green) and N: FoxP3+ (blue) cells. O: Overlay demonstrates absence of FoxP3 expression from IL-17+ cells (arrowheads demonstrate IL-17+ cells and arrows demonstrate FoxP3+ cells). Scale bar = 10 μm.