Figure 6.

Cell types and their distribution in ligation-injured carotid arteries. Arteries were harvested from CRPtg (top) versus CRPtg/FcγRI^−/− mice (bottom) 28 days after ligation injury, processed, and stained for immunoperoxidase-based detection of mouse F4/80 (monocytes/macrophages), B220 (B-cells), and CD4/CD8 (T cells). Mostly circulating monocytes and lymphocytes (punctuate staining) are seen in the patent vessels of CRPtg/FcγRI^−/−, whereas in the more occluded vessels of CRPtg, these were fewer in number, and there were more cells within the proliferative area (stellate/diffuse staining). Importantly all three cell types were found in both genotypes. Original magnifications, ×20.