Table 1.

Effect of rimonabant on body weight (Δ%) in control and CFA-injected rats

	Lean rat	Obese rat
Controls	2.60±2.08	0.59±0.84
Controls+ R 3 mg kg−1	−1.05±0.75	−6.50±0.79*
Controls+ R 10 mg kg−1	−0.95±1.37	−7.09±0.50*
CFA	0.94±0.79	−0.75±0.27
CFA+ R 3 mg kg−1	2.59±0.82	−8.13±0.34°
CFA+ R 10 mg kg−1	−2.79±1.20	−9.52±0.45°

Abbreviation: CFA, complete Freund's adjuvant.

Data are mean±s.e.m. from 5 to 12 rats. Body weight was expressed as a Δ% from mean body weight of day 7. Rats body weight was on day 0: 320±3.3 g lean, 514.0±6.1 g obese; on day 7 after CFA injection was 314.0±0.9 g lean controls, 311.0±0.87 g lean CFA, 518.0±7.8 g obese control, 507.7±4.5 g obese CFA.

^*P<0.05 vs controls

^°P<0.05 vs CFA (one-way ANOVA plus Newman–Keuls' test).