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. 2007 Jan 22;150(5):613–623. doi: 10.1038/sj.bjp.0707133

Figure 7.

Figure 7

[35S]GTPγS binding to membranes from hCB2-CHO cell membranes. The effect of (a) 1 μM cannabidiol (n=4–5), (b) 100 nM SR144528 (n=5–6) or (c) 1 μM O-2654 (n=3–5) on the mean log concentration–response curve of CP55940 for stimulation of [35S]GTPγS binding to CB2-transfected CHO cell membranes. Each symbol represents the mean percentage increase in [35S]GTPγS binding±s.e.m. Mean apparent KB values of these cannabinoids for their antagonism of CP55940 have been calculated from these data and are listed in Table 1.