Table 2.

Effects of antagonists at TP and EP1 receptors on the response to A23187 in quiescent femoral arteries 12 weeks after the injection of streptozotocin

	Control	S18886 (0.1 μM)	AH6809 (30 μM)	SC19220 (0.1 mM)	SC18886+AH6809+SC19220
Emax (% of 60 mM KCl)	112.77±4.95	70.70±13.60	69.08±9.95	52.74±13.54*	37.00±11.54*
pEC50 (−log M)	6.84±0.12	6.66±0.12	6.56±0.12	6.57±0.12	6.44±0.12

Abbreviations: EP-receptor, prostaglandin receptors E; TP, thromboxane-prostanoid.

Data shown as means±s.e.m.; n=6–9.

^*Statistically significant differences with control rings in the presence of L-NAME (one-way ANOVA; P<0.05).