Table 2.
Studies comparing expression of KP/KISS1 (GPR54) in metastatic and non-metastatic tumours across a variety of cancer types
| Cancer type | Changes in KP/KISS1 (GPR54) in metastatic tumours | Reference |
|---|---|---|
| Bladder cancer | Decreased KP | Sanchez-Carbayo et al. (2003b) |
| Breast carcinoma | Decreased KP | Lee and Welch (1997); Mitchell et al. (2006) |
| Choriocarcinoma | Decreased KP and KISS1 (GPR54) | Janneau et al. (2002) |
| Colon cancer | Not measured | Wisotzkey et al. (1997) |
| Endometrial carcinoma | Decreased KP, no change in KISS1 (GPR54) | Jiang et al. (2005) |
| Oesophageal carcinoma | Decreased KP and KISS1 (GPR54) | Ikeguchi et al. (2004) |
| Gastric carcinoma | Decreased KP | Dhar et al. (2004) |
| Hepatocellular carcinoma | Increased KP and KISS1 (GPR54) | Ikeguchi et al. (2003) |
| Malignant melanoma | Decreased KP | Lee et al. (1996); Shirasaki et al. (2001); Hesling et al. (2004) |
| Osteosarcoma | Decreased KP | Sanchez-Carbayo et al. (2003a) |
| Ovarian cancer | Decreased KP | Ohtaki et al. (2001) |
| Pancreatic cancer | Decreased KP, no change in KISS1 (GPR54) | Masui et al. (2004) |
| Papillary thyroid cancer | Decreased KP, increased KISS1 (GPR54) | Ringel et al. (2002) |