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Effects of guanethidine or capsaicin on vasodilation induced by nicotine (a), (−)-cytisine (b) and (±)-epibatidine (c) in rat perfused mesenteric vascular beds. The presence of guanethidine (5 μM) or treatment with capsaicin (1 μM) blocked the vasodilator effects of all three nicotinic agonists. **P<0.01, compared with control (without treatment).
