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Effects of mecamylamine on vasodilation induced by nicotine (a and b), (−)-cytisine (c) and (±)-epibatidine (d) in rat perfused mesenteric vascular beds. Mecamylamine at concentrations of 1 or 10 μM blocked the vasodilator effects of all three nicotinic agonists. **P<0.01, compared with control (without antagonist).
