Effects of dihydro-beta-erythroidine (DHβE; 1 and 10 μM) (a), α-bungarotoxin (100 nM) (b) and methyllycaconitine (MLA; 10 nM, 1 and 10 μM) (c) on the nicotine-induced vasodilation in rat perfused mesenteric vascular beds. Here, DHβE (a), α-bungarotoxin (b) and MLA (c) did not affect vasodilation induced by nicotine. Note however that, at high concentrations, MLA did show some antagonism of the nicotine effect. **P<0.01, compared with control (without antagonist).