Figure 6.
Effects of adrenalectomy or RU 38486 treatment on expression of adhesion molecules on endothelial cell membranes. Vehicle-treated (VT) or RU 38486 was administered for 7 days (10 mg kg−1, i.p., every 24 h). Cremaster muscle was collected 24 h after the last doses of vehicle or RU 38486 or 7 days after adrenalectomy or sham surgery. Data and immunohistochemistry images were obtained from non-manipulated (NM), sham-operated (SO), Vehicle (VT), adrenalectomized (ADX) or RU 38486-treated rats. a=PECAM; b=ICAM-1; c=VCAM=1. Results are expressed as the mean±s.e.mean of three assays performed in quadruplicate. Bar=10 μm. *P<0.05 vs controls.