Table 4.
Preprandial vs postprandial healthy volunteers
| Age (years) | BMI | Gender | Glucose (mM) | Insulin | C peptide | Leptin | Triglycerides | Total cholesterol | HDL | LDL | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Preprandial healthy volunteers means (n=12)±s.e.mean | 32.3±3.9 | 21.7±2.9 | 8M/4F | 4.61±0.05 | 4.02±0.63 | 417.83±46.92 | 7.92±1.21 | 0.71±0.12 | 1.76±0.06 | 0.57±0.05 | 1.05±0.05 |
| Postprandial healthy volunteers means (n=12)±s.e.mean | 5.06±0.22* | 25.2±6.47*** | 1587.25±216.05*** | 7.67±1.33 | 1.1±0.19**** | 1.76±0.05 | 0.56±0.04 | 1.02±0.05 |
Abbreviations: BMI, body mass index, expressed in kg m−2; HDL, high-density lipoprotein; LDL, low-density lipoprotein, OEA, oleoylethanolamide; PEA, palmitoylethanolamide.
This experiment was designed to assess whether or not a transient hyperglycaemia, corrected by well functioning insulin signalling, results in decreased serum OEA and PEA levels. Blood sampling was carried out 1 h before and after the meal, respectively. *,***,****P<0.05, 0.005, 0.0005, respectively vs paired volunteers, as assessed by the two-tailed paired Student's test. Insulin is expressed in mU ml−1. C peptide is expressed in pmol l−1. Leptin is expressed in ng ml−1. Triglycerides, total cholesterol, HDL and LDL are expressed in g l−1.