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Effect of URB602 (10 mg kg−1 i.p.), administered in a therapeutic regimen, on (a) oedema and (b) thermal hypersensitivity, evaluated 2 h (oedema) or 5 h (thermal hypersensitivity) and 24 h after carrageenan. Data represent mean±s.e.m. of 8–10 mice. ***P<0.001, **P<0.01, *P<0.05 versus non-inflamed; °°°P<0.001, °°P<0.01 versus inflamed. URB602, [1,1′-biphenyl]-3-yl-carbamic acid, cyclohexyl ester.
