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Extinction of WIN55,212-2 (WIN) self-administration in Long Evans (LE; left panel) and Lister Hooded (LH; right panel) female and male rats. Values are expressed as the number of active lever-presses (mean±s.e.mean) during each daily 2-h session. BASAL=mean value of active responses during the last 3 days of cannabinoid intake (end of the maintenance phase). Each group included seven animals. ***P<0.001 vs corresponding values for males.
