Effect of WIN55,212-2 (1 μM) in the presence of a CB1 cannabinoid receptor antagonist, LY320135 (a), and CB2 receptor antagonist, SR144528 (b), on contractile responses to EFS (5–40 Hz, 1 ms, 90 V, 30 s) in the perfused mesenteric vascular bed of rat with tone raised by U46619. Data are shown as mean±s.e.m. (n=4–6). *P<0.05 vs control groups (ANOVA). ANOVA, analysis of variance; EFS, electrical field stimulation.