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Mesenteric resistance artery vasodilation to atypical cannabinoids is not different between tissues from WT and GPR55 KO mice
| Compound | EC50 (μM) | Rmax (% reversal of PE pre-constriction) | EC50 (μM) | Rmax (% reversal of PE pre-constriction) |
|---|---|---|---|---|
| Abnormal cannabidiol | 3.0±0.6 | 107±5 | 2.6±0.5 | 99±4 |
| O-1602 | 2.8±0.3 | 101±2 | 2.2±0.4 | 95±7 |
Abbreviations: GPR55 KO, mice homozygous for the GPR55 mutation; WT, wild-type littermate controls for GPR55 KO mice.
