. Author manuscript; available in PMC: 2008 Jan 10.

Published in final edited form as: Hepatology. 2007 Nov;46(5):1464–1475. doi: 10.1002/hep.21887

Table 4.

Studies Evaluating BM Derivation of Liver Endothelium After Transplantation

Study	Species	Percentage of BM-Derived LSECs	Techniques Used	Microscopy	LSEC Marker	BM Marker
Gao et al.³⁶	Human, mouse	Identified, not quantified	X-Y mismatched sex, IHC	Light	Factor VIII	Y,X chromosome
Ng et al.³⁷	Human	<1%	X-Y mismatched sex, IHC	Epifluorescence	CD31	Y,X chromosome
Hove et al.³⁸	Human	Identified, not quantified	X-Y mismatched sex, recipient HLA, IHC	Light, IHC	Factor VIII	Y,X chromosome
Pons et al.³⁹	Human	51 ± 8.28	X-Y mismatched sex, FISH	Epifluorescence	vWF	Y,X chromosome
Present study	Rat	2%–5%	WT graft to EGFP recipient, mismatched recipient MHC	Confocal immunofluorescence, immuno-SEM, flow cytometry	SE-1 fenestrations	Recipient MHC class, EGFP

Abbreviation: IHC, immunohistochemistry.