Table 9.
Association between bacteraemia and clinical failure in children aged 2-59 months receiving ampicillin plus gentamicin for very severe pneumonia
| Variable | Treatment failures in children with bacteraemia | Treatment failures in children without bacteraemia | Relative risk (95% CI) |
|---|---|---|---|
| Any bacteraemia | |||
| Follow-up: | n=54 | n=425 | |
| 48 hours | 2 (4) | 30 (7) | 0.52 (0.13 to 2.13) |
| 5 days | 7 (13) | 44 (10) | 1.25 (0.59 to 2.64) |
| 10 days | 7 (13) | 55 (13) | 1.00 (0.48 to 2.09) |
| 21 days | 9 (17) | 63 (15) | 1.12 (0.59 to 2.13) |
| Death | 4 (7) | 21 (5) | 1.50 (0.53 to 4.20) |
| Staphylococcus aureus bacteraemia | |||
| Follow-up: | n=21 | n=458 | |
| 48 hours | 0 | 32 (7) | — |
| 5 days | 2 (6) | 49 (11) | 0.89 (0.23 to 3.42) |
| 10 days | 2 (6) | 60 (13) | 0.73 (0.19 to 2.77) |
| 21 days | 3 (14) | 69 (15) | 0.95 (0.33 to 2.76) |
| Death | 0 | 25 (6) | |
| Streptococcus pneumoniae bacteraemia | |||
| Follow-up: | n=12 | n=467 | |
| 48 hours | 0 | 32 (7) | — |
| 5 days | 0 | 51 (11) | — |
| 10 days | 0 | 62 (13) | — |
| 21 days | 1 (8) | 71 (15) | 0.55 (0.08 to 3.62) |
| Death | 1 (8) | 24 (5) | 1.62 (0.24 to 11.02) |