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Odds Ratio and Half-Time of Biophase Distribution (T1/2,ke0) Estimates (95% CI) Obtained From the Logistic Regression Pharmacodynamic Analysis for Buprenorphine and Fentanyl
| T1/2,ke0 (min) | Buprenorphine | Fentanyl |
|---|---|---|
| Antinociception | 86.4 (71.3–101.5) | 6.08 (4.43–7.73) |
| Respiratory depression | 109 (49–169) | 1.97 (−0.32–4.26) |
| Odds ratio | ||
| Antinociception | 28.5 (6.9–50.1) | 3.03 (1.87–4.21) |
| Respiratory depression | 2.10 (0.71–3.49) | 2.54 (1.26–3.82) |
