Table 2.

MT-binding- and MT assembly-promoting properties of normal and mutant tau

	MT binding		MT assembly promotion
	Bmax, μM*	Kd, μM*	Lag time, ∼min	Initiation rate, OD/min	A350 max
Normal	1.238  ±  0.042	0.039  ±  0.006	2	0.15	0.534  ±  0.014
279K	1.265  ±  0.055	0.056  ±  0.012	2	0.16	0.557  ±  0.005
Δ280K	1.011  ±  0.080	0.1526  ±  0.035†	5	0.14	0.472  ±  0.006†
301L	0.883  ±  0.047†	0.079  ±  0.016‡	5	0.14	0.518  ±  0.012
305N	1.184  ±  0.166	0.063  ±  0.026	2	0.15	0.529  ±  0.011

B_max, k_d, values are given as mean ± SEM.  

^†, p < 0.01;  

^‡, p < 0.05.