Table 1.

Genes up-regulated in the absence of EKLF

Gene symbols	Gene name	Ratio of WT to KO (P)
ITGA2B	Integrin α 2b	0.4 (<.001)
VWF	Von Willebrand factor homolog	0.3 (<.001)
FLI1	Friend leukemia integration 1	0.4 (.004)
PF4 (CXCL4)	Platelet factor 4	0.5 (.006)
THBS1	Thrombospondin 1	0.3 (.001)
PECAM	Platelet/endothelial cell adhesion molecule	0.4 (.007)

High-density oligonucleotide microarrays (Affymetrix, Santa Clara, CA) were analyzed with RNA from wild-type (WT) and EKLF-null (KO) E13.5 fetal livers (M. Arcosoy and P.G.G., manuscript in preparation). Three independent RNA samples were analyzed. Expression levels of genes relevant to megakaryocyte expression are shown as a ratio between WT and KO levels, along with their P value. Relevant genes that were not affected include c-mpl, PBP (CXCL7), RANTES (CCL5), and ENA78 (CXCL5).