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. 2007 Oct 2;35(22):7429–7455. doi: 10.1093/nar/gkm711

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© 2007 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — (a) X-ray structure of the two-repeat human telomere bimolecular G-quadruplex formed by the d(TAGGGTTAGGGT) sequence for crystals grown from K⁺ solution (coordinates deposition: 1K8P) (17). The bases are color coded as follows: guanine (blue), adenine (green) and thymine (orange). All strands are parallel in this bimolecular quadruplex and the loops are of the double-chain-reversal or propeller type. NMR-based folding topologies of interconverting (b) all parallel-stranded and (c) anti-parallel-stranded conformations of the two-repeat human telomere bimolecular G-quadruplex formed by the d(TAGGGTTAGGGT) sequence in K⁺ solution (94).