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. Author manuscript; available in PMC: 2008 Mar 30.
Published in final edited form as: Auton Neurosci. 2007 Jul 5;137(1-2):19–26. doi: 10.1016/j.autneu.2007.05.005

Figure 5.

Figure 5

Response of pupil light reflex to pyridostigmine (A) Changes in peak relative constriction amplitude in control and EAAG rabbits after one dose of pyridostigmine and after 5 days of treatment. Control rabbits and low Ab EAAG rabbits did not show significant changes, although the pupil responses in 2 of the 4 low Ab EAAG rabbits improved. All three high Ab EAAG rabbits improved with pyridostigmine. (B) Representative tracings of pupil responses in a low Ab EAAG rabbit in which there was improvement of pupillary function with pyridostigmine treatment. After pyridostigmine (bottom trace), the initial pupil diameter was smaller, the constriction amplitude increased, and the pupil constriction continued throughout the stimulus (arrow).