Table 4.

Relationship of serum sex hormones/SHBG levels to serum lipids and triglycerides

Sex hormones	LDL-C (mg/dl)		HDL-C (mg/dl)		TG (mg/dl)
	β-Estimate	P value	β-Estimate	P value	β-Estimate	P value
Estrone (pg/ml)	−0.06 (0.01)	<0.0001	0.02 (0.002)	<0.0001	0.02 (0.01)	0.10
Total E2 (pg/ml)	−0.34 (0.03)	<0.0001	0.09 (0.01)	<0.0001	0.13 (0.08)	0.10
Free E2 (pg/ml)	−14.1 (1.4)	<0.0001	3.82 (0.57)	<0.0001	5.74 (3.1)	0.06
Total testosterone (ng/dl)	−0.12 (0.13)	0.34	0.11 (0.06)	0.07	−0.40 (0.36)	0.28
Free testosterone (pg/ml)	2.36 (0.77)	0.002	−1.36 (0.34)	<0.0001	0.20 (1.6)	0.93
Androstenedione (pg/ml)	0.001 (0.005)	0.83	−0.007 (0.002)	0.0005	0.004 (0.01)	0.79
DHEA (ng/ml)	2.5 (0.82)	0.002	−1.58 (0.38)	<0.0001	−1.15 (1.8)	0.52
SHBG (nmol/liter)	−0.41 (0.05)	<0.0001	0.15 (0.02)	<0.0001	−0.10 (0.13)	0.44

Generalized estimating equation models adjusted for age, BMI, and treatment group. E2, Estradiol.