. 2007 Oct 16;93(1):267–277. doi: 10.1210/jc.2007-0539

Table 2.

Relative mRNA expression of deiodinases and MCT8, and deiodinase activities, in the family-A proposita and control thyroid tissues.

Sample	Relative mRNA expression			Enzymatic activity
Sample	MCT8	D1	D2	D1 (pmol/min·mg protein)	D2 (fmol/h·mg protein)
Family A proposita	1.00 ± 0.05	1.00 ± 0.07	1.00 ± 0.08	70.7 ± 0.1	166.5 ± 34.9
1	0.93 ± 0.09	0.37 ± 0.05^a	0.54 ± 0.10^a	11.2 ± 1.6^a	86.3 ± 18.8^a
2	0.36 ± 0.03^a	0.11 ± 0.01^a	0.16 ± 0.12^a	ND	ND
3	0.45 ± 0.02^a	0.24 ± 0.01^a	0.21 ± 0.03^a	6.8 ± 0.3^a	32.5 ± 5.3^a
3T	0.99 ± 0.20	0.64 ± 0.11	0.29 ± 0.06^a	45.4 ± 3.8^a	132.9 ± 12
4T	1.09 ± 0.36	1.10 ± 0.20	0.37 ± 0.01^a	142 ± 4.3^b	180 ± 2
5	0.30 ± 0.03^a	0.26 ± 0.02^a	0.55 ± 0.10^a	24.7 ± 4.3^a	54.8 ± 22.7^a
6	1.63 ± 0.04^b	0.78 ± 0.07	0.59 ± 0.17	34.2 ± 4.1^a	150.7 ± 0.6
7	0.91 ± 0.01	0.55 ± 0.22	0.18 ± 0.14^a	ND	ND

Data are shown as means ± sd. Numbers 1–7 refer to healthy parts of surgically derived thyroid specimens. ND, Not done; T, thyroid tissue from inside a toxic adenoma.

P < 0.05 vs. family-A proposita.

P < 0.05 vs. family-A proposita with higher values than the family-A proposita.