Table 2.

Time constant values (τ) for time-dependent activation of different mutations at the upper Glycine hinge in heteromeric Kir4.1/Kir5.1 channels

	τ (s)		τ (s)
Kir4.1/Kir5.1	1.63 ± 0.16
Kir4.1(T154G)/Kir5.1	0.53 ± 0.02**	Kir4.1/Kir5.1(S157G)	1.59 ± 0.15
Kir4.1(T154V)/Kir5.1	0.82 ± 0.02**	Kir4.1/Kir5.1(S157V)	1.27 ± 0.05
Kir4.1(T154S)/Kir5.1	0.79 ± 0.09**	Kir4.1/Kir5.1(S157T)	1.25 ± 0.10
Kir4.1(T154A)/Kir5.1	0.72 ± 0.07**	Kir4.1/Kir5.1(S157A)	1.31 ± 0.04

The activation curves at −120 mV were fitted with a single exponential function

** P value < 0.05