Table 1.

Killing of 1106 mel cells correlated with high levels of CD16 expression on NK cells (measured with FITC-mAb 3G8 using FITC-IgG1 as a control)

Line	MFI		% lysis of 1106 mel
	Control	CD16
3G8 dim
E4	10	17	6
C1	11	25	5
C10	10	33	3
C11	10	36	2
G11	12	19	3
D12	9	41	3
D3	10	33	2
H1	11	28	12
Mean	10.3	29	4.5
3G8 bright
17	10	184	34
24	11	207	28
3–2	12	199	29
4–2	11	296	37
30	12	261	32
32	10	171	31
33	9	184	42
334	9	314	28
Mean	10.5	227	32.6

NK cells lines were sorted (30 cells per well) to be either 3G8 dim (upper half of the table) or 3G8 bright (lower half of the table). Median fluorescence intensity (MFI) was determined by using FACS analysis. Assays were performed at an E:T ratio of 2.5:1. The table shows one representative experiment out of three performed.