Table I.
Antigen-specific GC Numbers and Sizes in Msh2-deficient Mice
Total NP+ GCs per 10× field* | ||||||||
---|---|---|---|---|---|---|---|---|
Small | Medium | Large | ||||||
Day 8 | ||||||||
+/+ | 2.2 ± 1.6 | 3.5 ± 2.17 | 1.2 ± 0.98‡ | |||||
Total | 6.83 ± 2.56 | |||||||
+/− | 3.83 ± 1.17 | 2.33 ± 1.03 | 0.5 ± 0.84 | |||||
Total | 6.67 ± 2.25 | |||||||
−/− | 3.33 ± 2.07 | 3.33 ± 2.58 | 0‡ | |||||
Total | 6.67 ± 1.37 | |||||||
Day 12 | ||||||||
+/+ | 2.17 ± 1.17 | 1.83 ± 0.75 | 1.67 ± 1.33¶+ | |||||
Total | 5.67 ± 1.5 § ** | |||||||
+/− | 3.25 ± 1.89 | 1.25 ± 1.26 | 0.25 ± 0.5¶ | |||||
Total | 4.75 ± 1.70 ‖ ** | |||||||
−/− | 1.67 ± 1.5 | 2.0 ± 1.41 | 0+ | |||||
Total | 3.67 ± 1.37 § ‖ |
Values were obtained from three mice of each genotype. Two random fields per section and two sections per mouse from different areas of the single spleen were analyzed.
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, +Value pairs that pass the Student's t test at the 90% confidence level.