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. 1999 Feb 1;189(3):531–540. doi: 10.1084/jem.189.3.531

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Delineation of T cell determinants on hRo60 in mice of different haplotypes. In vitro LNC proliferative responses were recalled, with synthetic peptides at 20 μM concentration. Results are expressed as SI, a ratio of the mean triplicate CPM obtained with peptide and the mean triplicate cpm without peptide. (A) Multiple determinants recognized by SJL/J T cells are present in Ro60. Results are shown as mean triplicate SI ± SEM from three independent experiments. Peptides giving an SI > 2 are marked with an asterisk (*). For comparison, the response to rhRo60 at a concentration of 3 μg/ml is shown. (B) A summary of T cell determinants on hRo60, seen by SJL/J, A/J, and BALB/c mice. Amino acid sequences for peptides giving a SI > 2 are shown.