Figure 4.
Normal induction of P1A-specific transgenic T cells. (a) Proliferation of spleen cells from transgenic and wild-type mice to tumor antigen P1A peptide or control peptide from influenza virus nucleoprotein (NP). (b) Cytotoxicity of transgenic T cells against J558-B7 or J558-Neo tumor cells. P388D1 cells (H–2d) pulsed with either P1A or NP (1 μg/ml) were used as controls. Transgenic spleen cells were stimulated for 72 h with P1A peptide and used as effectors.