Figure 1.
Depletion of macrophages in NOD mice by treatment with lip-Cl2MDP results in the prevention of diabetes. 12 3-wk-old female NOD mice were treated weekly with 200 μl of lip-Cl2MDP (•) until 20 wk of age; 10 female NOD mice were treated similarly with PBS (○). The cumulative incidence of diabetes was measured.