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. 1999 Jan 18;189(2):347–358. doi: 10.1084/jem.189.2.347

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Depletion of macrophages in NOD mice results in the failure of adoptive transfer of diabetes to NOD.scid mice by splenocytes. NOD.scid mice (6–8-wk-old) received splenocytes (2 × 10⁷ cells) isolated from 20-wk-old lip-Cl₂MDP–treated (n = 6, •) or PBS-treated (n = 6, ○) NOD mice or from newly diabetic (n = 7, ▴) NOD mice.