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. 1999 Apr 19;189(8):1243–1253. doi: 10.1084/jem.189.8.1243

Figure 8.

Figure 8

A model for how GrpL may function in TCR- mediated signal transduction. Results from our study demonstrate that GrpL and Grb2 may differentially associate with SLP-76, LAT/pp36/p38, and Sos1/2, respectively. The preferential interaction between GrpL and SLP-76 suggests that GrpL may play a role in the regulation NF-AT pathway during TCR-mediated T cell activation.