Figure 1.
Alignment of amino acid sequences of HLA-Cw6, -Cw7, -G, -A2, and the chimera HLA-Cw6/TM G used in the current study. The location of the Bsu36I restriction site used to make the chimeras HLA-Cw6/G end and HLA-Cw7/G end is marked. Residues underlined were those mutated into stop codons in HLA-Cw6, and the cysteine at position 309 that was mutated into tryptophan is marked bold and underlined. The region of HLA-Cw6 altered to make HLA-Cw6/TM G is shaded.