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. 1999 Apr 19;189(8):1169–1180. doi: 10.1084/jem.189.8.1169

Table I.

Histological Scoring System Used in TNBS-induced Colitis

Histological changes Scores
0 1 2
Crypt distortion None Focal Numerous or diffuse
Crypt with loss of goblet cells None A few crypts Many crypts
Acute inflammation (ulcers with infiltration of  polymorphonuclear cells) None Superficial Beyond the layer of Muscularis mucosae
Chronic inflammation (infiltration of mononuclear  cells and fibrosis in the mucosal layer) No increase Focal Multifocal