Table I.
Histological Scoring System Used in TNBS-induced Colitis
Histological changes | Scores | |||||
---|---|---|---|---|---|---|
0 | 1 | 2 | ||||
Crypt distortion | None | Focal | Numerous or diffuse | |||
Crypt with loss of goblet cells | None | A few crypts | Many crypts | |||
Acute inflammation (ulcers with infiltration of polymorphonuclear cells) | None | Superficial | Beyond the layer of Muscularis mucosae | |||
Chronic inflammation (infiltration of mononuclear cells and fibrosis in the mucosal layer) | No increase | Focal | Multifocal |