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. 1999 Mar 15;189(6):931–938. doi: 10.1084/jem.189.6.931

Figure 1.

Figure 1

Time course of MABP over the course of hemorrhage and reinfusion for the five experimental groups of mice. Wild-type and P-selectin–deficient (P-selectin−/−) mice were subjected to hemorrhagic shock. Functional blockade of P-selectin in wild-type mice was achieved by systemic administration of either anti–P-selectin mAb (1 mg/kg) or rs.PSGL.Ig (1 mg/kg). Each point represents mean values ± SEM; numbers indicate surviving rats at each interval. *P < 0.05 and **P < 0.01 versus wild-type control mice. □, control wild-type (n = 6); ▪, hemorrhage wild-type (n = 7); •, hemorrhage P-selectin−/− (n = 6); ○, hemorrhage wild-type + anti–P-selectin mAb (n = 5); ⋄, hemorrhage wild-type + rs.PSGL.Ig (n = 5).