Table I.
Diameters and Shear Rates for Mouse Peri-intestinal Venules
| Group | n | Venular diameter | Venular shear rate (s−1) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Baseline (0 min) | Hemorrhage (45 min) | Resuscitation (90 min) | ||||||||
| Control wild-type | 6 | 35 ± 3.3 | 620 ± 19 | 612 ± 33 | 563 ± 42 | |||||
| Hemorrhage P-selectin gene deleted | 7 | 33 ± 2.7 | 653 ± 20 | 320 ± 41 | 625 ± 40 | |||||
| Hemorrhage wild-type | 6 | 31 ± 6.3 | 616 ± 39 | 303 ± 28 | 618 ± 46 | |||||
| Hemorrhage wild-type + anti–P-selectin mAb | 5 | 36 ± 6.5 | 614 ± 41 | 310 ± 51 | 609 ± 37 | |||||
| Hemorrhage wild-type + rs.PSGL.Ig | 5 | 32 ± 8.1 | 626 ± 54 | 287 ± 47 | 617 ± 24 | |||||
All values are means ± SEM. n = numbers of mice studied.