Figure 11.
Inhibitory effect of PT on T cell transmigration through HUVEC monolayers and migration into collagen gels impregnated with anti-4C8 mAb. T cells were pretreated for 1 h with PT (100 ng/ml), washed three times, and cultured for 2 h with IFN-γ–stimulated HUVEC monolayers (A) or for 3 h on collagen gels with or without impregnated anti-4C8 (10 μg/ml; B). Adhesion and migration are expressed as the adhesion and the migration index, respectively. The data are presented as the mean ± SD of three independent experiments.