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. 1999 Jun 7;189(11):1783–1789. doi: 10.1084/jem.189.11.1783

Figure 4.

Figure 4

Trx does not increase cytosolic Ca2+ in human monocytes or PMNs. Traces represent levels of [Ca2+]i in single adherent monocytes (A and B) or PMNs (C and D) in response to 30 ng/ml (2.5 nM) Trx (A and C), 25 ng/ml (3 nM) IL-8 (D), or 50 ng/ml (6 nM) MCP-1 (B). Traces are representative of 12–32 cell recordings (7 donors, 3–5 cells per coverslip). Arrows indicate the addition of agents to the bathing medium, which causes a spike in the trace due to exposure to light.