Table II.
Trx Does Not Induce Increase of Ca2+ in Single Monocytes and PMNs
| Responsive cells | Mean Ca2+ increase | |||
|---|---|---|---|---|
| Monocytes | % | |||
| Trx 0.83–8.3 nM | 0 | 0 | ||
| MCP-1 3 nM | 82 | 227 ± 81 | ||
| FMLP 100 nM | 100 | 310 ± 41 | ||
| PMNs | ||||
| Trx 0.83–8.3 nM | 0 | 0 | ||
| IL-8 3 nM | 67 | 218 ± 64 | ||
| FMLP 100 nM | 100 | 260 ± 103 |
Data are cumulative of 15–30 cells analyzed. Cells were considered responsive when the stimulus-induced increase of [Ca2+]i was twice the SD over the mean of baseline values. Mean Ca2+ increase is the mean ± SD of values of responsive cells. Data are expressed as percentage above basal [Ca2+]i.