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Examples of spleen cell metaphases stained to visualize sister chromatid exchanges. wt metaphase, unirradiated. G6 mTR−/− metaphase, unirradiated. SCEs can be seen at points at which dark and light staining exchanges between chromatids. Frequencies of baseline and gamma radiation–induced SCE in wt and G6 mTR−/− splenocytes are also shown. 25 metaphases scored per treatment.
